Found 41 matching trials
Phase II Study Investigating the Combination of Encorafenib and Binimetinib in BRAF V600E Mutated Chinese Patients With Metastatic Non-Small Cell Lung Cancer PHASE2 This is a phase 2, multicenter, single-arm study with a safety lead-in to i...
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Location
Beijing Cancer Hospital
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MEK Inhibitor 162 Relapsed and/or Refractory Acute Myeloid Leukemia (AML) and Poor Prognosis, Not Suitable for or Unwilling to Receive Standard Therapy PHASE1 The goal of Phase 1 of this clinical research study is to find the highest ...
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University of Texas MD Anderson Cancer Center
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Melanoma Metastasized to the Brain and Steroids PHASE2 This clinical trial is to clarify whether treatment with a checkpoint inhib...
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Herlev Universityhospital
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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial PHASE2 This ComboMATCH patient screening trial is the gateway to a coordinated set...
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University of Alabama at Birmingham Cancer Center
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MEK Inhibitor MEK162, Idarubicin, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia PHASE1 This phase I trial studies the MEK inhibitor MEK162 to see if it is safe in...
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Stanford University, School of Medicine
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A Study of MEK162 vs. Physician's Choice Chemotherapy in Patients With Low-grade Serous Ovarian, Fallopian Tube or Peritoneal Cancer PHASE3 The MILO Study (MEK Inhibitor in Low-grade Serous Ovarian Cancer) is a Phas...
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University of Arizona Cancer Center
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Circulating Tumour DNA Guided Adaptive BRAF and MEK Inhibitor Therapy PHASE2 The goal of this clinical trial is to investigate adaptive therapy in late-...
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Multiple Locations
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Binimetinib and Encorafenib for the Treatment of Advanced Solid Tumors With Non-V600E BRAF Mutations PHASE2 This is a single-centre, open-label Phase II study of the investigational d...
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Active Not Recruiting
Location
Princess Margaret Cancer Centre
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Perioperative Encobini in BRAFV600 Mutant Stage III (B/C/D) or Oligometastatic Stage IV Melanoma PHASE2 A two-arm, randomised trial investigating the response of encorafenib and b...
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Addenbrooke's Hospital
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A Study of ARRY-438162 (MEK162) in Patients With Advanced Cancer PHASE1 This is a Phase 1 study during which patients with advanced solid tumors wi...
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University of California, Los Angeles
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